The Incredible Story behind ‘The Frozen Addicts’

English: MPPP; 1-methyl-4-phenyl-4-propionoxyp...

MPPP; 1-methyl-4-phenyl-4-propionoxypiperidine, desmethylprodine Deutsch: 1-Methyl-4-phenyl-4-propion-oxy-piperidin; 3-Desmethylprodin or synthetic heroin -however one mistake in the lab and it becomes an injectable nightmare.  (Photo credit: Wikipedia)

A nightmare of immense proportions for any opiate user watching this film. Watch the simply mindblowing film about a handful of opiate users in California in the early 1980′s who, after injecting what they thought was heroin, woke up completely frozen – in body and voice – but not mind. Locked into a prison of their own bodies, their stories confounded doctors until bit by bit they managed to unravel what had happened to them and so began the long, long road as they endeavored to cure them of their condition, despite at times creating other situations that were as bad if not worse than the original Parkinson-like condition they initially faced.

Crucially, I think it is worth mentioning that the underground chemist who was trying to manufactuer a synthetic form of heroin known as MPPP, rushed the process and came up with something called MPTP, a drug that destroyed peoples dopamine receptors, leaving them unable to produce dopamine and thus leaving them frozen in their bodies. See text below the video for link to information on MPTP and MPPP. This is yet another byproduct of prohibition, where the law allows underground labs to flourish and horrendous mistakes like this to occur. This is not to say mistakes don’t occur in big pharma although in general, research techniques ensure such enormous problems are found before such drugs find their way to market. You can also follow up the stories of these amazing individuals whom our hearts go out to, on google etc.

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NOTE on MPPP and MTPT: While MPTP itself has no psychoactive effects, the compound may be accidentally produced during the manufacture ofMPPP, a synthetic opioid drug with effects similar to those of morphine and pethidine (meperidine). The Parkinson-inducing effects of MPTP were first discovered following accidental ingestion as a result of contaminated MPPP. For more info on MPTP and MPPP, click here.

Krokodil- Home made heroin of the very worst kind

Viktor Ivanov, the head of Russia's Drug Control Agency

Viktor Ivanov, the head of Russia's Drug Control Agency

I am reprinting here an Independent article from June on what is perhaps one of the most disturbing issues to confront the drug using community in years. Home made heroin – desomorphine (also called Krokodil because of what it does to the skin) is becoming more and more common in Russia, affecting the poorest heroin users and having the most horrendous effects on the body. The Russian government continues to look the other way, refusing to provide methadone or subutex or humane and evidenced based treatments. Their lame attempt at banning one of the ingredients (over the counter sales of codeine)will do little to circumvent what is fast becoming an epidemic of home made drugs of dire quality. Please read this article and check out our videos down the right hand side of the page on the effects of desomorphine.Note: desomorphine was apparently invented in the USA in 1923 as a pharmaceutical preparation and was used in Switzerland under the trade name Permonid (strong opiate, fast onset, short duration). Krokodil and desomorphine as home made in Russia, seems more to pertain to the extremely hazardous way it is made, using ingrdients as mentioned below – and not in the sterile pharmy environment that desomorphine could in fact be made, without all the added human health problems associated with it. Worrying, Krokodil, the ‘home made’ desomorphine, has recently spread to Germany. Unless someone makes Russia listen soon and implement harm reduction such as OST, Needle exchange, etc -we are going to see this death and destruction of lives continue to spread further than Russia.

Krokodil: The drug that eats junkies  (Click link for the original Independant article June 22nd 2011)

A home-made heroin substitute is having a horrific effect on thousands of Russia’s drug addicts

By Shaun Walker

Oleg glances furtively around him and, confident that nobody is watching, slips inside the entrance to a decaying Soviet-era block of flats, where Sasha is waiting for him. Ensconced in the dingy kitchen of one of the apartments, they empty the contents of a blue carrier bag that Oleg has brought with him – painkillers, iodine, lighter fluid, industrial cleaning oil, and an array of vials, syringes, and cooking implements.

Half an hour later, after much boiling, distilling, mixing and shaking, what remains is a caramel-coloured gunge held in the end of a syringe, and the acrid smell of burnt iodine in the air. Sasha fixes a dirty needle to the syringe and looks for a vein in his bruised forearm. After some time, he finds a suitable place, and hands the syringe to Oleg, telling him to inject the fluid. He closes his eyes, and takes the hit.

Russia has more heroin users than any other country in the world – up to two million, according to unofficial estimates. For most, their lot is a life of crime, stints in prison, probable contraction of HIV and hepatitis C, and an early death. As efforts to stem the flow of Afghan heroin into Russia bring some limited success, and the street price of the drug goes up, for those addicts who can’t afford their next hit, an even more terrifying spectre has raised its head.

(See video on vod pod – bottom right column)

The home-made drug that Oleg and Sasha inject is known as krokodil, or “crocodile”. It is desomorphine, a synthetic opiate many times more powerful than heroin that is created from a complex chain of mixing and chemical reactions, which the addicts perform from memory several times a day. While heroin costs from £20 to £60 per dose, desomorphine can be “cooked” from codeine-based headache pills that cost £2 per pack, and other household ingredients available cheaply from the markets.

It is a drug for the poor, and its effects are horrific. It was given its reptilian name because its poisonous ingredients quickly turn the skin scaly. Worse follows. Oleg and Sasha have not been using for long, but Oleg has rotting sores on the back of his neck.

“If you miss the vein, that’s an abscess straight away,” says Sasha. Essentially, they are injecting poison directly into their flesh. One of their friends, in a neighbouring apartment block, is further down the line.

“She won’t go to hospital, she just keeps injecting. Her flesh is falling off and she can hardly move anymore,” says Sasha. Photographs of late-stage krokodil addicts are disturbing in the extreme. Flesh goes grey and peels away to leave bones exposed. People literally rot to death.

Russian heroin addicts first discovered how to make krokodil around four years ago, and there has been a steady rise in consumption, with a sudden peak in recent months. “Over the past five years, sales of codeine-based tablets have grown by dozens of times,” says Viktor Ivanov, the head of Russia’s Drug Control Agency. “It’s pretty obvious that it’s not because everyone has suddenly developed headaches.”

Heroin addiction kills 30,000 people per year in Russia – a third of global deaths from the drug – but now there is the added problem of krokodil. Mr Ivanov recalled a recent visit to a drug-treatment centre in Western Siberia. “They told me that two years ago almost all their drug users used heroin,” said the drugs tsar. “Now, more than half of them are on desomorphine.”

He estimates that overall, around 5 per cent of Russian drug users are on krokodil and other home-made drugs, which works out at about 100,000 people. It’s a huge, hidden epidemic – worse in the really isolated parts of Russia where supplies of heroin are patchy – but palpable even in cities such as Tver.

It has a population of half a million, and is a couple of hours by train from Moscow, en route to St Petersburg. Its city centre, sat on the River Volga, is lined with pretty, Tsarist-era buildings, but the suburbs are miserable. People sit on cracked wooden benches in a weed-infested “park”, gulping cans of Jaguar, an alcoholic energy drink. In the background, there are rows of crumbling apartment blocks. The shops and restaurants of Moscow are a world away; for a treat, people take the bus to the McDonald’s by the train station.

In the city’s main drug treatment centre, Artyom Yegorov talks of the devastation that krokodil is causing. “Desomorphine causes the strongest levels of addiction, and is the hardest to cure,” says the young doctor, sitting in a treatment room in the scruffy clinic, below a picture of Hugh Laurie as Dr House.

“With heroin withdrawal, the main symptoms last for five to 10 days. After that there is still a big danger of relapse but the physical pain will be gone. With krokodil, the pain can last up to a month, and it’s unbearable. They have to be injected with extremely strong tranquilisers just to keep them from passing out from the pain.”

Dr Yegorov says krokodil users are instantly identifiable because of their smell. “It’s that smell of iodine that infuses all their clothes,” he says. “There’s no way to wash it out, all you can do is burn the clothes. Any flat that has been used as a krokodil cooking house is best forgotten about as a place to live. You’ll never get that smell out of the flat.”

Addicts in Tver say they never have any problems buying the key ingredient for krokodil – codeine pills, which are sold without prescription. “Once I was trying to buy four packs, and the woman told me they could only sell two to any one person,” recalls one, with a laugh. “So I bought two packs, then came back five minutes later and bought another two. Other than that, they never refuse to sell it to us, even though they know what we’re going to do with it.” The solution, to many, is obvious: ban the sale of codeine tablets, or at least make them prescription-only. But despite the authorities being aware of the problem for well over a year, nothing has been done.

President Dmitry Medvedev has called for websites which explain how to make krokodil to be closed down, but he has not ordered the banning of the pills. Last month, a spokesman for the ministry of health said that there were plans to make codeine-based tablets available only on prescription, but that it was impossible to introduce the measure quickly. Opponents claim lobbying by pharmaceutical companies has caused the inaction.

“A year ago we said that we need to introduce prescriptions,” says Mr Ivanov. “These tablets don’t cost much but the profit margins are high. Some pharmacies make up to 25 per cent of their profits from the sale of these tablets. It’s not in the interests of pharmaceutical companies or pharmacies themselves to stop this, so the government needs to use its power to regulate their sale.”

In addition to krokodil, there are reports of drug users injecting other artificial mixes, and the latest street drug is tropicamide. Used as eye drops by ophthalmologists to dilate the pupils during eye examinations, Dr Yegorov says patients have no trouble getting hold of capsules of it for about £2 per vial. Injected, the drug has severe psychiatric effects and brings on suicidal feelings.

“Addicts are being sold drugs by normal Russian women working in pharmacies, who know exactly what they’ll be used for,” said Yevgeny Roizman, an anti-drugs activist who was one of the first to talk publicly about the krokodil issue earlier this year. “Selling them to boys the same age as their own sons. Russians are killing Russians.”

Zhenya, quietly spoken and wearing dark glasses, agrees to tell his story while I sit in the back of his car in a lay-by on the outskirts of Tver. He managed to kick the habit, after spending weeks at a detox clinic ,experiencing horrendous withdrawal symptoms that included seizures, a 40-degree temperature and vomiting. He lost 14 teeth after his gums rotted away, and contracted hepatitis C.

But his fate is essentially a miraculous escape – after all, he’s still alive. Zhenya is from a small town outside Tver, and was a heroin addict for a decade before he moved onto krokodil a year ago. Of the ten friends he started injecting heroin with a decade ago, seven are dead.

Unlike heroin, where the hit can last for several hours, a krokodil high only lasts between 90 minutes and two hours, says Zhenya. Given that the “cooking” process takes at least half an hour, being a krokodil addict is basically a full-time job.

“I remember one day, we cooked for three days straight,” says one of Zhenya’s friends. “You don’t sleep much when you’re on krokodil, as you need to wake up every couple of hours for another hit. At the time we were cooking it at our place, and loads of people came round and pitched in. For three days we just kept on making it. By the end, we all staggered out yellow, exhausted and stinking of iodine.”

In Tver, most krokodil users inject the drug only when they run out of money for heroin. As soon as they earn or steal enough, they go back to heroin. In other more isolated regions of Russia, where heroin is more expensive and people are poorer, the problem is worse. People become full-time krokodil addicts, giving them a life expectancy of less than a year.

Zhenya says every single addict he knows in his town has moved from heroin to krokodil, because it’s cheaper and easier to get hold of. “You can feel how disgusting it is when you’re doing it,” he recalls. “You’re dreaming of heroin, of something that feels clean and not like poison. But you can’t afford it, so you keep doing the krokodil. Until you die.”

Some of the names in this story have been changed

Missing Sebastian Horsley

Sebastian Reading Black Poppy

Sebastian Reading Black Poppy

Today as I was doing the final proofread for our newest issue, I was weighed down by re-reading my interview piece about Sebastian Horsley. He was such a warm and witty person, a Dandy personified; I just wanted to put in a few of his thoughts that I couldn’t fit in our article. Some will irritate, some will shock, but Sebastian said it like it was for him; he wasn’t afraid to be disliked, though he loved to be loved, he was a misfit – like us – and he saw that in our eyes, as much as we understood that in his.

Note: Sebastian died in June – a few days after his play, based on his book, Dandy in the Underworld opened in the West End.

Emails…..

Erin: “I have to say it is so refreshing to see someone live their life authentically, being true, individual; romantic and vulnerable. Fuckin brilliant I say! Fill your life with your own meaning and colours, not others.

Sebastian: That is such a beautiful sentence thank you Erin. I have tried not to be a hypocrite. I have tried not to build walls around myself. I have tried to live the truth of my life and it sometimes makes others question theirs. You see I am no different than them, I just choose to be honest about it. And you have done the same. But they call it immorality and are jealous because we dare to live whilst they have not the guts. But that is England for you.I cannot tell you how warming it is to meet kindred spirits. I choose life because I have no alternative, because I know that after death there is nothing at all. An affirmation of individual life, in itself and for itself, desirable because it is “absurd”, without final meaning or metaphysical justification. I can’t wait to receive the copies especially our one! And to see you at the play, My Love as Ever. Sx

Sebastian re a date for chat and tea: I suggest tea at  Saturday 20th say 2.00pm  Horsley Towers. 7 Meard Street.  Heterosexual tea, kinky tea, G& T, or notoriety? Although of course you know my favourite? Insincerity. Roughly when will this be published my dear so I know what to wear? Looking forward to seeing you and meeting Lisa. And being photographed by her. I like her website and am sure I can add to it with my gorgeousness, ha ha!

“Maybe I would like to get high with myself.  Still i find the allure of narcotics more exciting than sex, which is strange.”

Sebastian to friend (forwarded back to me from Seb): I just did an interview Black Poppy. How could I resist? “The Heroin Users Health & Lifestyle Magazine.” Priceless! Now isn’t that genuinely subversive in a pathetically non-subversive age? It rather be in that than any of those wanker Guardian/Observer broadsheets. Erin didn’t pay me but being on the cover is payment enough I’d say. Yes she is well. I really love her and I admire so much what they do. It is isn’t in my nature to support any cause or group but I support them with everything. Like you, I’m just so glad people like that exist. NOTHING LIKE THAT EXISTS ANYMORE APART FROM CUNTS LIKE US.

Sebastian: on Heroin

I always love the smell of heroin in the morning. Smells like … victory. SH

Everything was going to be all right. A coal fire on a stormy night, rain that could not touch me beating against the window pane. Streams made of smoke, and smoke that formed into shinning pools. Thoughts shimmering on the borders of a languorous hallucination.

Heroin is the only thing that really works, the only thing that stops you scampering around in a hamster’s wheel of unanswerable questions. Heroin is the cavalry. Heroin is the missing chair leg, made with such precision that it matched every splinter of the break. Heroin landed purring at the base of my skull, and wrapped itself darkly around my nervous system, like  a black cat curling up on its favourite cushion. It is as soft and rich as the throat of a wood pigeon, or the splash of sealing wax onto a page, or a handful of gems slipping from palm to palm.

On drugs you know you’re happy. Heroin easily makes do without people. Out of almost nothing it creates a presence. It gives the gift of life. It  imparts depth and beauty to all, drawing it together, providing atmosphere, charm and intimacy with all the palpitations of life. It creates an illusion. It creates the illusion.

Sebastian says in our interview that he couldn’t use and work – “I would like to be able to take drugs and work, but for me its a very simple exchange; it’s taken me a long time and a lot of mistakes to work it out; if I take heroin and crack that’s all I will do, I cant do anything else. If i don’t take C&H I can do anything I want – apart from that.”

Look out for one of the last Horsley interviews in BPs next issue no 14. Funny, witty and kind, he will be really, really missed.

For SH’s Images, click here

Erin O

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